An increasing prevalence of hospital acquired infections and foodborne illnesses caused by pathogenic and multidrug resistant bacteria has stimulated a pressing need for benchtop computational methods to rapidly and accurately classify bacteria from genomic sequence data, and based on that, to trace the source of infection.

BacWGSTdb aims to provide a one-stop solution to epidemiological outbreak analysis and pioneer the movement of whole genome sequencing (WGS) from proof-of-concept studies to routine use in the clinical microbiology laboratory. Bench scientists can also use this database as a convenient tool for phylogenetic analysis of bacterial genomes.

Update News

  • 05-18

    2019

    BacWGSTdb 2.0 development finished and new website released.

  • 12-18

    2018

    Added bacterial source tracking with cgMLST/wgMLST strategy.

  • 06-18

    2018

    BacWGSTdb 2.0 project launched and 11 new species were incorporated.

  • 09-23

    2015

    BacWGSTdb 1.0 paper was accepted by Nucleic Acids Research.

  • 06-18

    2015

    BacWGSTdb 1.0 development finished and formally online.

  • 01-28

    2015

    BacWGSTdb 1.0 project launched.

Contact information

Citations:

Zhi Ruan, Ye Feng. BacWGSTdb, a database for genotyping and source tracking bacterial pathogens, Nucleic Acids Research. 2016; 44(D1): D682-D687.

Zhi Ruan, Yunsong Yu, Ye Feng. The global dissemination of bacterial infections necessitates the study of reverse genomic epidemiology, Briefings in Bioinformatics. 2019; doi: 10.1093/bib/bbz010. [Epub ahead of print]